Epigenetics as a first exit problem.
نویسندگان
چکیده
We develop a framework to discuss the stability of epigenetic states as first exit problems in dynamical systems with noise. We consider in particular the stability of the lysogenic state of the lambda prophage. The formalism defines a quantitative measure of robustness of inherited states.
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ورودعنوان ژورنال:
- Physical review letters
دوره 88 4 شماره
صفحات -
تاریخ انتشار 2002